ECOFIT H20™ Science

shown to reduce systemic inflammation by 39% – 53%Capros Superfruit
Capros is also known as Emblica Officinalis, Amla or Indian gooseberry and is one of the most antioxidant rich superfruits in the world. It has primarily been used to promote all facets of health.

Capros Is backed by human clinical studies that:
Support healthy aging by reducing systemic inflammation in the body.
Support cardiovascular health.
Support immune system health.
Support mental stress management.
Support a natural nitric oxide boost in the body.

* 12 Week Capros Trial Overview

Reducing Systemic Inflammation – Reducing Oxidative Stress – Increasing Nitric Oxide

● During this 12-week trial, Capros showed significant improvement in endothelial function, oxidative stress, immune response, and lipid profile.

● Out of the 65 screened subjects, 59 eligible subjects were randomized and completed the study.

● The study consisted of two different dosages of Phyllanthus emblica extract (Capros) – 250 mg and 500 mg twice daily. Both dosages showed significant improvement in endothelial function (cardiovascular health), oxidative stress biomarkers-Nitric oxide (+ 41.89%, + 50.7%), Glutathione (+ 24.31%, + 53.22%), Malondialdehyde (- 21.02%, – 31.44%), and systemic inflammation biomarker, hsCRP (- 39.68%, – 53.77%) at 12 weeks with 250 mg and 500 mg twice daily dosage respectively, compared to baseline and placebo.

● Results also showed a significant mean percent change at 12 weeks with total cholesterol (- 7.71%, – 11.11%), HDL-C (+ 7.33% + 22.16%), LDL-C (- 11.39%, – 21.8%) and Triglycerides (- 9.81%, – 19.22%) respectively with 250 mg and 500 mg twice daily. The 500 mg twice daily dose was significantly more efficacious than the 250 mg twice daily dose and placebo.
                                                                                                                                                                                                                                                                                      

Healthy Immune Response

Capros Amla is standardized to potent polyphenols, including hydrolysable tannins, emblicanin A, emblicanin B, punigluconin and pedunculagin. Polyphenols are powerful antioxidants found in a variety of plant extracts that have been shown to support cognitive health, digestion, heart health and a healthy immune response. These polyphenols have been shown to support the immune system by modulating ROS and lipid peroxidation. Tannins, found in Capros, have been shown to impact ROS, MDA, antioxidant GSH and cytokine production. Polyphenol bioavailability, including tannins, is typically very low due to limited absorption, extensive metabolism and rapid excretion. Capros’ unique aqueous extract preserves the polyphenols and at 500 mg (250 mg twice a day) ensures cardio benefits indirectly supporting a healthy immune response. In addition to heart health, Capros further supports the body’s natural balance by protecting the body against oxidative stress and supports a healthy immune response without being a pro-oxidant.

Cardiovascular Health

Acute and chronic stress is a risk factor for the development and progression of coronary artery disease. Increased arterial stiffness is an independent marker for cardiovascular disease. Cold pressor test (CPT) is known to be associated with substantial activation of the autonomic nervous system.

Objective
The aim of this study was to evaluate the effect of Phyllanthus emblica extract (Capros) on cold pressor stress test induced changes on cardiovascular parameters and aortic wave reflections in healthy human subjects.

Materials and Methods
● This was a double-blind, placebo-controlled, crossover study. Participants were randomized to receive either two capsules of P. emblica extract 250 mg (containing aqueous extract of P. emblica, highly standardized by high-performance liquid chromatography to contain low molecular weight hydrolysable tannins emblicanin-A, emblicanin-B, pedunculagin and punigluconin) or two capsules of placebo twice daily for 14 days.

● Pharmacodynamic parameters such as heart rate, augmentation pressure, augmentation index (AIx), subendocardial viability ratio (SEVR), radial and aortic blood pressure (BP) were recorded before and after CPT at baseline and end of treatment.

● After a washout period of 14 days, subjects crossed over to the other treatment and the same test procedure was repeated again. Safety assessments were done at baseline and at the end of treatment.

Results
A total of 12 volunteers completed the study. Compared with baseline and placebo, P. emblica extract produced a significant decrease of mean percent change in the indices of arterial stiffness (AIx, radial and aortic BP) and increase in SEVR, an index of myocardial perfusion with CPT. Both treatments were well-tolerated and no serious adverse events
were reported.
                                                                                                                                                                                                                                                                                      

Mental Stress Management

Introduction
Experimental studies have found that acute stress leads to pathophysiological changes in cardiac risk profile and thereby more directly explain a link to cardiovascular disease. The present study was undertaken to evaluate the effect of Emblica officinalis (Capros) versus placebo on mental stress induced changes in cardiovascular hemodynamic parameters and arterial wave reflection properties in healthy human subjects.

Materials & Methods
In this randomized, double-blind, placebo-controlled, crossover study, participants received either two capsules of standardized Emblica officinalis fruit extract 250 mg or placebo daily for 2 weeks, as per prior randomization schedule. Pharmacodynamic parameters were recorded before and after a standardized mental stress test, at baseline and at the end of treatment. After a 2-week washout, participants crossed over to receive the other treatment.

Results
A total of 12 volunteers completed the study. Compared to baseline, Emblica officinalis fruit extract produced a statistically significant decrease in Aortic augmentation pressure (from 6.6±2.15 to 4.6±2.02); (p< 0.01) and in Augmentation Index AIx (from 120.1±12.80 to 116.2±12.63); (p< 0.05). There was a reduction in Radial and Aortic systolic (SBP) and diastolic (DBP) pressures and an increase in Sub Endocardial Viability Ratio (SEVR), which was however not statistically significant.

Conclusion
Acute mental stress results in temporary increase in arterial stiffness and wave stiffness. Standardized Emblica officinalis fruit extract decreased the mental stress induced changes on aortic wave reflections in normal healthy subjects. These results suggest the beneficial effect of Emblica officinalis in mitigating the effects of stress, thereby reducing the risk of acute cardiovascular morbidity.

* Understanding The Capros Clinical Study
As you read about the clinical studies conducted on Capros, it is important to understand that ECOFIT H20™ uses 250 mg of Capros in each 16 oz bottle. To achieve the desired results and health benefits, participants were given 250 mg and 500mg once and twice a day. Please understand that those daily dosages were used to determine those clinical health benefits.

Drinking 1 to 2 bottles a day of ECOFIT H20™ shown to reduce systemic inflammation by 39% – 53%, boosts nitric oxide by 41% – 50%, supports immune system health, supports cardiovascular health and mental stress management.

MAGNESIUM
ECOFIT H20™ leads with magnesium as the major trace mineral/electrolyte in our drink. The role of magnesium in our bodies cannot be understated. Magnesium is the fourth most abundant mineral in the body and participates in over 300 biochemical reactions. It also fuels digestive enzymes to help the body effectively process carbohydrates, proteins, and fats. Magnesium also plays a key role in nerve conduction, muscle contraction, bone and tooth formation, and heart and circulatory health. In addition, magnesium is essential in the production of ATP, the energy storage molecule in the body. Magnesium also supports sleep, stress, and contributes to flexibility by loosening tight muscles, which also help reduce injury when exercising.

Unfortunately, some research has concluded that about 68% of Americans don’t consume the recommended daily intake of magnesium. The adult Recommended Dietary Allowance (RDA) for magnesium is 350 mg per day for men and 280 mg per day for women.

ECOFIT H20™ helps solve this problem by delivering 150 mg of magnesium from a natural source in each 16oz bottle.

CALCIUM
ECOFIT H20™ contains calcium, which supports healthy skin, the heart, strong bones and teeth. It also helps reduce leg cramps and supports muscular functions.

POTASSIUM
ECOFIT H20™ contains potassium, which supports energy production and helps maintain water balance within the cells; it also helps control nerve impulses.

SODIUM
ECOFIT H20™ contains sodium, which supports fluid control in the body and supports nerve and muscle functions.

ZINC
ECOFIT H20™ contains zinc, which supports immune system health, healthy skin, taste, smell, hair and nails.

CHLORIDE
ECOFIT H20™ contains chloride, which happens to be one of the main electrolytes lost in sweat, especially during prolonged exertion in warm and hot environments.

VITAMIN B3
ECOFIT H20™ contains vitamin b3, which supports healthy energy and cholesterol levels.

VITAMIN B5
ECOFIT H20™ contains vitamin b5, which supports stress levels and helps prevent fatigue.

VITAMIN B6
ECOFIT H20™ contains vitamin b6, which supports immune system health and helps reduce muscle cramps.

VITAMIN B12
ECOFIT H20™ contains vitamin b12, which supports memory, energy levels and concentration.

TRACE MINERALS
Your body is an intricate circuit board of electric charges and impulses. In order for it to stay balanced and perform at optimum efficiency, you need to constantly replenish yourself with the trace minerals found in ECOFIT H20™. If you are one of the 90% of Americans experts estimate to suffer mineral imbalance or deficiency, your body is lacking these essential elements, causing your body to misfire and make you feel rundown and tired.

Many people overestimate the importance of trace minerals for the human body. They are the catalysts for all the vitamins and other nutrients your body uses for developing and maintaining good health. Consuming trace minerals every day may help maintain healthy energy levels in your body by providing your body’s entire electrical system the minerals it needs to function properly.